Intermediate-Frail and Frail Elderly Men? Composition, And Quality of Life Persist Six Months after Treatment in Do the Effects of Testosterone on Muscle Strength, Physical Function, Body
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Re: do the effects of testosterone on muscle strength, physical function, body composition, and quality of life persist six months after treatment in intermediate-frail and frail elderly men?
CONTEXT Short-term testosterone (T) treatment in frail elderly men improves muscle mass and strength. It is unclear whether these effects can be maintained post treatment. OBJECTIVE To assess the durability of androgen effects in frail men. DESIGN AND SETTING Single center, randomized, double-blind, placebo-controlled trial to investigate the effects of 6 months T (25-75 mg daily) on muscle...
متن کاملEffects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study.
CONTEXT Physical frailty is associated with reduced muscle strength, impaired physical function, and quality of life. Testosterone (T) increases muscle mass and strength in hypogonadal patients. It is unclear whether T has similar effects in intermediate-frail and frail elderly men with low to borderline-low T. OBJECTIVE Our objective was to determine the effects of 6 months T treatment in in...
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Background and objectives: Up-to-date, no studies have assessed phenotypes of frail in the elderly people living in Tehran and their relationships with nutritional statuses. The aim of this study was to investigate prevalence of frailty and its relationships with malnutrition in elderly people living in Tehran, 2021–2022. Materials and Methods: In this cross-sectional study, 508 elderly people ...
متن کاملTestosterone Deficiency and Testosterone Treatment in Older Men.
Frailty is a clinical condition related to changes in metabolism, to sarcopenia, and to decline in muscle mass and strength, bone mineral density, and physical function with aging. The pathophysiology of frailty is multifactorial and associated with comorbidities. Testosterone is implicated in regulating metabolic functions, maintenance of muscle and bone, and inhibition of adipogenesis. In old...
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CONTEXT Hip fractures are common in the elderly, and despite standard rehabilitation, many patients fail to regain their prefracture ambulatory or functional status. OBJECTIVE To determine whether extended outpatient rehabilitation that includes progressive resistance training improves physical function and reduces disability compared with low-intensity home exercise among physically frail el...
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